[Continued from yesterday. P.G.] Though a bitter cold day, yet I rose, and though my pain and tenderness in my testicle remains a little, yet I do verily think that my pain yesterday was nothing else, and therefore I hope my disease of the stone may not return to me, but void itself in pissing, which God grant, but I will consult my physitian. This morning is brought me to the office the sad newes of “The London,” in which Sir J. Lawson’s men were all bringing her from Chatham to the Hope, and thence he was to go to sea in her; but a little a’this side the buoy of the Nower, she suddenly blew up. About 24 [men] and a woman that were in the round-house and coach saved; the rest, being above 300, drowned: the ship breaking all in pieces, with 80 pieces of brass ordnance. She lies sunk, with her round- house above water. Sir J. Lawson hath a great loss in this of so many good chosen men, and many relations among them. I went to the ‘Change, where the news taken very much to heart. So home to dinner, and Mr. Moore with me. Then I to Gresham College, and there saw several pretty experiments, and so home and to my office, and at night about 11 home to supper and to bed.