This text was copied from Wikipedia on 25 November 2022 at 6:01AM.
An enema, also known as a clyster, is an injection of fluid into the lower bowel by way of the rectum. The word enema can also refer to the liquid injected, as well as to a device for administering such an injection.
In standard medicine, the most frequent uses of enemas are to relieve constipation and for bowel cleansing before a medical examination or procedure; also, they are employed as a lower gastrointestinal series (also called a barium enema), to treat traveler's diarrhea, as a vehicle for the administration of food, water or medicine, as a stimulant to the general system, as a local application and, more rarely, as a means of reducing temperature, as treatment for encopresis, and as a form of rehydration therapy (proctoclysis) in patients for whom intravenous therapy is not applicable.
In other contexts, enemas are used by some alternative health therapies, used for enjoyment, chiefly as part of sexual activities, but also in BDSM, as well as simply for pleasure, used to intoxicate with alcohol, used to administer drugs for both recreational and religious reasons, and used for punishment.
- 1 Medical usage
- 1.1 Bowel cleansing
- 1.1.1 Acute treatments
- 1.1.2 Chronic treatments
- 1.2 Contrast (X-ray)
- 1.3 Medication administration
- 1.4 Inhibiting pathological defecation
- 1.5 Other
- 1.1 Bowel cleansing
- 2 Adverse effects
- 3 History
- 4 Society and culture
- 4.1 Alternative medicine
- 4.2 Recreational usage
- 4.3 Religious rituals
- 4.4 Punitive usage
- 4.5 In arts and literature
- 5 See also
- 6 References
- 7 External links
The principal medical usages of enemas are:
As bowel stimulants, enemas are employed for the same purposes as orally administered laxatives: To relieve constipation; To treat fecal impaction; To empty the colon prior to a medical procedure such as a colonoscopy. When oral laxatives are not indicated or are not sufficiently effective, enemas may be a sensible and necessary measure.
A large volume of enema can be given to cleanse as much of the colon as possible of feces. However, a low enema is generally useful only for stool in the rectum, not in the intestinal tract.
Such enemas' mechanism consists of the volume of the liquid causing rapid expansion of the intestinal tract in conjunction with, in the case of certain solutions, irritation of the intestinal mucosa which stimulates peristalsis and lubricates the stool to encourage a bowel movement. An enema's efficacy depends on several factors including the volume injected and the temperature and the contents of the infusion. In order for the enema to be effective the patient should retain the solution for five to ten minutes, as tolerated. or, as some nursing textbooks recommend, for five to fifteen minutes or as long as possible.
Large volume enemas
For emptying the entire colon as much as feasible deeper and higher enemas are utilized to reach large sections of the colon. The colon dilates and expands when a large volume of liquid is injected into it, and the colon reacts to that sudden expansion with general contractions, peristalsis, propelling its contents toward the rectum.
Soapsuds enema is a frequently used synonym for a large volume enema (although soap is not necessary for effectivity).
For relieving occasional constipation, a large volume enema may be used in a home setting, although for recurring or severe cases of constipation medical care may be required.
Plain water can be used, simply functioning mechanically to expand the colon, thus prompting evacuation.
Normal saline is least irritating to the colon. Like plain water, it simply functions mechanically to expand the colon, but having a neutral concentration gradient, it neither draws electrolytes from the body, as happens with plain water, nor draws water into the colon, as occurs with phosphates. Thus, a salt water solution can be used when a longer period of retention is desired, such as to soften an impaction.
Equal parts of milk and molasses heated together to slightly above normal body temperature have been used. Neither the milk sugars and proteins nor the molasses are absorbed in the lower intestine, thus keeping the water from the enema in the intestine. Studies have shown that milk and molasses enemas have a low complication rate when used in the emergency department and are safe and effective with minimal side effects.
ATC codes for drugs for constipation — enemas
|A Alimentary tract and metabolism|
|A01 Stomatological preparations|
|A02 Drugs for acid related disorders|
|A03 Drugs for functional gastrointestinal disorders|
|A04 Antiemetics and antinauseants|
|A05 Bile and liver therapy|
|A06 Drugs for constipation|
|A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents|
|A08 Antiobesity preparations, excluding diet products|
|A09 Digestives, including enzymes|
|A10 Drugs used in diabetes|
|A12 Mineral supplements|
|A14 Anabolic agents for systemic use|
|A15 Appetite stimulants|
|A16 Other alimentary tract and metabolism products|
ATC code A06 Drugs for constipation is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. Subgroup A06 is part of the anatomical group A Alimentary tract and metabolism.
Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QA06.
National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.
- A06AG01 Sodium phosphate
- A06AG02 Bisacodyl
- A06AG03 Dantron, including combinations
- A06AG04 Glycerol
- A06AG06 Oil
- A06AG07 Sorbitol
- A06AG10 Docusate sodium, including combinations
- A06AG11 Sodium lauryl sulfoacetate, including combinations
- A06AG20 Combinations
Single substance solutions
This section needs expansion. You can help by adding to it. (March 2019)
In alphabetical order
Dantron is a stimulant drug and stool softener used alone or in combinations in enemas. Considered to be a carcinogen its use is limited, e.g., restricted in the UK to patients who already have a diagnosis of terminal cancer and not used at all in the USA.
Glycerol has a hyperosmotic effect and can be used as a small-volume (2–10 ml) enema (or suppository).
Sodium phosphate. Also known by the brand name Fleet. Available at drugstores; usually self-administered. Buffered sodium phosphate solution draws additional water from the bloodstream into the colon to increase the effectiveness of the enema. But it can be rather irritating to the colon, causing intense cramping or "griping." Fleet enemas usually causes a bowel movement in 1 to 5 minutes. Known adverse effects.
Sorbitol pulls water into the large intestines causing distention, thereby stimulating the normal forward movement of the bowels. Sorbitol is found in some dried fruits and may contribute to the laxative effects of prunes. and is available for taking orally as a laxative. As an enema for constipation, the recommended adult dose is 120 mL of 25-30% solution, administered once. Note that Sorbitol is an ingredient of the MICROLAX Enema.
Compounded from multiple ingredients
This section needs expansion. You can help by adding to it. (March 2019)
In alphabetical order of the original brand names
Klyx contains docusate sodium 1 mg/mL and sorbitol solution (70%) (crystallising) 357 mg/mL and is used for faecal impaction or constipation or for colon evacuation prior medical procedures, developed by Ferring B.V.
Micralax (not to be confused with MICROLAX®)
MICROLAX® (not to be confused with Micralax) combines the action of sodium citrate, a peptidising agent which can displace bound water present in the faeces, with sodium alkyl sulphoacetate, a wetting agent, and with glycerol, an anal mucosa irritant and hyperosmotic. However, also sold under the name "Micralax", is a preparation containing sorbitol rather than glycerol; which was initially tested in preparation for sigmoidoscopy.
Micolette Micro-enema® contains 45 mg sodium lauryl sulphoacetate, 450 mg per 5 ml sodium citrate BP, and 625 mg glycerol BP and is a small volume stimulant enema suitable where large-volume enemas are contra-indicated.
TAI, also termed retrograde irrigation, is designed to assist evacuation using a water enema as a treatment for persons with bowel dysfunction, including fecal incontinence or constipation, especially obstructed defecation. By regularly emptying the bowel using transanal irrigation, controlled bowel function is often re-established to a high degree, thus enabling development of a consistent bowel routine. Its effectiveness varies considerably, some individuals experiencing complete control of incontinence but others reporting little or no benefit.
An international consensus on when and how to use transanal irrigation for people with bowel problems was published in 2013, offering practitioners a clear, comprehensive and simple guide to practice for the emerging therapeutic area of transanal irrigation.
The term retrograde irrigation distinguishes this procedure from the Malone antegrade continence enema, where irrigation fluid is introduced into the colon proximal to the anus via a surgically created irrigation port.
Patients who have a bowel disability, a medical condition which impairs control of defecation, e.g., fecal incontinence or constipation, can use bowel management techniques to choose a predictable time and place to evacuate. Without bowel management, such persons might either suffer from the feeling of not getting relief, or they might soil themselves.
While simple techniques might include a controlled diet and establishing a toilet routine, a daily enema can be taken to empty the colon, thus preventing unwanted and uncontrolled bowel movements that day.
In a lower gastrointestinal series an enema that may contain barium sulfate powder or a water-soluble contrast agent is used in the radiological imaging of the bowel. Called a barium enema, such enemas are sometimes the only practical way to view the colon in a relatively safe manner.
Failure to expel all of the barium may cause constipation or possible impaction and a patient who has no bowel movement for more than two days or is unable to pass gas rectally should promptly inform a physician and may require an enema or laxative.
The administration of substances into the bloodstream. This may be done in situations where it is undesirable or impossible to deliver a medication by mouth, such as antiemetics given to reduce nausea (though not many antiemetics are delivered by enema). Additionally, several anti-angiogenic agents, which work better without digestion, can be safely administered via a gentle enema.
The topical administration of medications into the rectum, such as corticosteroids and mesalazine used in the treatment of inflammatory bowel disease. Administration by enema avoids having the medication pass through the entire gastrointestinal tract, therefore simplifying the delivery of the medication to the affected area and limiting the amount that is absorbed into the bloodstream.
Rectal corticosteroid enemas are sometimes used to treat mild or moderate ulcerative colitis. They also may be used along with systemic (oral or injection) corticosteroids or other medicines to treat severe disease or mild to moderate disease that has spread too far to be treated effectively by medicine inserted into the rectum alone.
Inhibiting pathological defecation
- Traveller's diarrhea's symptoms treated with an enema of sodium butyrate, organic acids, and A-300 silicon dioxide can be successfully decreased with lack of observed side effects.
- Shigellosis treatment benefits from adjunct therapy with butyrate enemas, promoting healing of the rectal mucosa and inflammation, but not helping in clinical recovery from shigellosis. Use of an 80 ml of a sodium butyrate isotonic enema administered every 12 hours has been studied and found effective.
- There have been a few cases in remote or rural settings, where rectal fluids have been used to rehydrate a person. Benefits include not needing to use sterile fluids.
- Introducing healthy bacterial flora through infusion of stool, known as a fecal microbiota transplant, was first performed in 1958 employing retention enemas. Enemas remained the most common method until 1989, when alternative means of administration were developed. As of 2013, colonoscope implantation has been preferred over fecal enemas because by using the former method, the entire colon and ileum can be inoculated, but enemas reach only to the splenic flexure.
- A patient unable to be fed otherwise can be nourished by an enteral administration of predigested foods, which is known as a nutrient enema. This treatment is ancient, dating back at least to the second century CE when documented by Galen, and commonly used in the Middle Ages, remaining a common technique in 19th century, and as recently as 1941 the U. S. military's manual for hospital diets prescribes their use. Nutrient enemas have been superseded in modern medical care by tube feeding and intravenous feeding.
- Enemas have been used around the time of childbirth; however, there is no evidence for this practice and it is now discouraged.
Improper administration of an enema can cause electrolyte imbalance (with repeated enemas) or ruptures to the bowel or rectal tissues resulting in internal bleeding. However, these occurrences are rare in healthy, sober adults. Internal bleeding or rupture may leave the individual exposed to infections from intestinal bacteria. Blood resulting from tears in the colon may not always be visible, but can be distinguished if the feces are unusually dark or have a red hue. If intestinal rupture is suspected, medical assistance should be obtained immediately. Frequent use of enemas can cause laxative dependency.
There are arguments both for and against colonic irrigation in people with diverticulitis, ulcerative colitis, Crohn's disease, severe or internal hemorrhoids or tumors in the rectum or colon, and its usage is not recommended soon after bowel surgery (unless directed by one's health care provider). Regular treatments should be avoided by people with heart disease or kidney failure. Colonics are inappropriate for people with bowel, rectal or anal pathologies where the pathology contributes to the risk of bowel perforation.
A recent case series of 11 patients with five deaths illustrated the danger of phosphate enemas in high-risk patients.
Enema entered the English language c. 1675 from Latin in which, in the 15th century, it was first used in the sense of a rectal injection, from Greek ἔνεμα (énema), "injection", itself from ἐνίηναι (enienai) "to send in, inject", from ἐν (en), "in" + ἱέναι (hienai), "to send, throw".
Clyster entered the English language in the late 14th century from Old French or Latin, from Greek κλυστήρ (klyster), "syringe", itself from κλύζειν (klyzein), "to wash out", also spelled glister in the 18th century, is a generally archaic word used more particularly for enemas administered using a clyster syringe.
Ancient and medieval
The first mention of the enema in medical literature is in the Ancient Egyptian Ebers Papyrus (c. 1550 BCE). One of the many types of medical specialists was an Iri, the Shepherd of the Anus. Many medications were administered by enemas. There was a Keeper of the Royal Rectum who may have primarily been the pharaoh's enema maker. The god Thoth, according to Egyptian mythology, invented the enema.
In parts of Africa the calabash gourd is used traditionally to administer enemas. On the Ivory Coast the narrow neck of the gourd filled with water is inserted the patient's rectum and the contents are then injected by means of an attendant's forcible oral inflation, or, alternatively, a patient may self-administer the enema by using suction to create a negative pressure in the gourd, placing a finger at the opening, and then upon anal insertion, removing the finger to allow atmospheric pressure to effect the flow. Along the upper Congo River an enema apparatus is made by making a hole in one end of the gourd for filling it, and using a resin to attach a hollow cane to the gourd's neck. The cane is inserted into the anus of the patient who is in a posture that allows gravity to effect infusion of the fluid.
The Olmec from their middle preclassic period (10th through 7th centuries BCE) through the Spanish Conquest used trance-inducing substances ceremonially, and these were ingested via, among other routes, enemas administered using jars.
As further described below in religious rituals, the Maya in their late classic age (7th through 10th centuries CE) used enemas for, at least, ritual purposes, Mayan sculpture and ceramics from that period depicting scenes in which, injected by syringes made of gourd and clay, ritual hallucinogenic enemas were taken. In the Xibalban court of the God D, whose worship included ritual cult paraphernal, the Maya illustrated the use of a characteristic enema bulb syringe by female attendants administering clysters ritually.
A rubber bag connected with a conical nozzle, at an early period, was in use among the indigenous peoples of South America as an enema syringe, and the rubber enema bag with a connecting tube and ivory tip remained in use by them while in Europe a syringe was still the usual means for conducting an enema.
In Babylonia, by 600 BCE, enemas were in use, although it appears that initially they were in use because of a belief that the demon of disease would, by means of an enema, be driven out of the body. Babylonian and Assyrian tablets c. 600 BCE bear cuneiform inscriptions referring to enemas.
In China, c. 200 CE, Zhang Zhongjing was the first to employ enemas. "Secure a large pig's bile and mix with a small quantity of vinegar. Insert a bamboo tube three or four inches long into the rectum and inject the mixture" are his directions, according to Wu Lien-teh.
In India, in the fifth century BCE, Sushruta enumerates the enema syringe among 121 surgical instruments described. Early Indian physicians' enema apparatus consisted of a tube of bamboo, ivory, or horn attached to the scrotum of a deer, goat, or ox.
In Persia, Avicenna (980–1037 A. D.) is credited with the introduction of the "clyster-purse" or collapsible portion of an enema outfit made from ox skin or silk cloth and emptied by squeezing with the hands.
Hippocrates (460–370 BCE) frequently mentions enemas, e.g., "if the previous food which the patient has recently eaten should not have gone down, give an enema if the patient be strong and in the prime of life, but if he be weak, a suppository should be administered, should the bowels be not well moved on their own accord."
In the first century BCE the Greek physician Asclepiades of Bithynia wrote "Treatment consists merely of three elements: drink, food, and the enema". Also, he contended that indigestion is caused by particles of food that are too big and his prescribed treatment was proper amounts of food and wine followed by an enema which would remove the improper food doing the damage.
In the second century CE the Greek physician Soranus prescribed, among other techniques, enemas as a safe abortion method, and the Greek philosopher Celsus recommended an enema of pearl barley in milk or rose oil with butter as a nutrient for those with dysentery and unable to eat, and also Galen mentions enemas in several contexts.
In medieval times appear the first illustrations of enema equipment in the Western world, a clyster syringe consisting of a tube attached to a pump action bulb made of a pig bladder. A simple piston syringe clyster was in use from the 15th through 19th centuries. This device had its rectal nozzle connected to a syringe with a plunger rather than to a bulb.
Beginning in the 17th century enema apparatus was chiefly designed for self-administration at home and many were French as enemas enjoyed wide usage in France.
In 1694 François Mauriceau in his early-modern treatise, The Diseases of Women with Child, records that both midwives and man-midwives commonly administered clysters to labouring mothers just prior to their delivery.
Clysters were administered for symptoms of constipation and, with more questionable effectiveness, stomach aches and other illnesses.
In 1753 an enema bag prepared from a pig's or beef's bladder attached to a tube was described by Johann Jacob Woyts as an alternative to a syringe.
In the 18th century Europeans began emulating the indigenous peoples of North America's use of tobacco smoke enemas to resuscitate drowned people. Tobacco resuscitation kits consisting of a pair of bellows and a tube were provided by the Royal Humane Society of London and placed at various points along the Thames. Furthermore, these enemas came to be employed for headaches, respiratory failure, colds, hernias, abdominal cramps, typhoid fever, and cholera outbreaks.
Clysters were a favourite medical treatment in the bourgeoisie and nobility of the Western world up to the 19th century. As medical knowledge was fairly limited at the time, purgative clysters were used for a wide variety of ailments, the foremost of which were stomach aches and constipation.
According to the duc de Saint-Simon, clysters were so popular at the court of King Louis XIV of France that the duchess of Burgundy had her servant give her a clyster in front of the King (her modesty being preserved by an adequate posture) before going to the comedy. However, he also mentions the astonishment of the King and Mme de Maintenon that she should take it before them.
In the 19th century many new types of enema administration equipment were devised. Devices allowing gravity to infuse the solution, like those mentioned above used by South American indigenous people and like the enema bag described by Johann Jacob Woyts, came into common use. These consist of a nozzle at the end of a hose which connects a reservoir, either a bucket or a rubber bag, which is filled with liquid and held or hung above the recipient.
Society and culture
The term "colonic irrigation" is commonly used in gastroenterology to refer to the practice of introducing water through a colostomy or a surgically constructed conduit as a treatment for constipation. The Food and Drug Administration has ruled that colonic irrigation equipment is not approved for sale for the purpose of general well-being and has taken action against many distributors of this equipment, including a Warning Letter.
The same term is also used in alternative medicine where it may involve the use of substances mixed with water in order to detoxify the body. Practitioners believe the accumulation of fecal matter in the large intestine leads to ill health. This resurrects the old medical concept of autointoxication which was orthodox doctrine up to the end of the 19th century but which has now been discredited.
In the late 19th century Dr. John Harvey Kellogg made sure that the bowel of each and every patient was plied with water, from above and below. His favorite device was an enema machine ("just like one I saw in Germany") that could run fifteen gallons of water through a person's bowel in a matter of seconds. Every water enema was followed by a pint of yogurt—half was eaten, the other half was administered by enema "thus planting the protective germs where they are most needed and may render most effective service." The yogurt served to replace "the intestinal flora" of the bowel, creating what Kellogg claimed was a completely clean intestine.
Chlorine dioxide enemas have been fraudulently marketed as a medical treatment, primarily for autism. This has resulted, for example, in a six-year-old boy needing to have his colon removed and a colostomy bag fitted, complaints to the FDA reporting life-threatening reactions, and even death.
Proponents falsely claim that administering autistic children these enemas results in the expulsion of parasitic worms ("rope worms"), which actually are fragments of damaged intestinal epithelium that are misinterpreted as being human pathogens. Oral and rectal use of the solution has also been promoted as a cure for HIV, malaria, viral hepatitis, influenza, common colds, acne, cancer, Parkinson's, and much more.
Chlorine dioxide is a potent and toxic bleach that is relabeled for "medicinal purposes" to a variety of brand names including, but not limited, to MMS, Miracle Mineral Supplement, and CD protocol. For oral use, the doses recommended on the labeling can cause nausea, vomiting, diarrhea, and potentially life-threatening dehydration.
No clinical trials have been performed to test the health claims made for chlorine dioxide, which originate from former Scientologist Jim Humble in his 2006 self-published book, The Miracle Mineral Solution of the 21st Century and from anecdotal reports. The name MMS was coined by Humble. Sellers sometimes describe MMS as a water purifier so as to circumvent medical regulations. The International Federation of Red Cross and Red Crescent Societies rejected "in the strongest terms" reports by promoters of MMS that they had used the product to fight malaria.
A coffee enema can cause numerous maladies including infections, sepsis (including campylobacter sepsis), severe electrolyte imbalance, colitis, polymicrobial enteric sepsis, proctocolitis, salmonella, brain abscess, and heart failure, and deaths related to coffee enemas have been documented.
Some proponents of alternative medicine have claimed that coffee enemas have an anti-cancer effect by "detoxifying" metabolic products of tumors but there is no medical scientific evidence to support this.
Both women and men may enjoy sexual enema play, heterosexually and homosexually, experiencing sexual arousal from enemas which they find gratifying or sensual and which can be an auxiliary to, or even a substitute for, genital sexual activity.
Klismaphiles may perceive pleasure from a large, water distended belly or the feeling of internal pressure. An enema fetish may include the sexual attraction to the equipment, processes, environments, situations, or scenarios, Klismaphiles can gain satisfaction of enemas through fantasies, by actually receiving or giving one, or through the process of eliminating steps to being administered one (e.g., under the pretence of being constipated).
That some women use enemas while masturbating was documented by Alfred Kinsey in "Sexual Behavior in the Human Female." He stated, "There still [are] other masturbatory techniques which were regularly or occasionally employed by some 11 percent of the females in the sample ... enemas, and other anal insertions, ... were employed."
Besides klismaphilia, the intrinsic enjoyment of enemas, there are other uses of enemas in sexual play.
This is different from klismaphilia, in which the enema is enjoyed for itself and as a part of sexual arousal and gratification.
Rectal douching is a common practice among people who take a receptive role in anal sex although rectal douching before anal sex may increase the risk of transferring HIV, hepatitis B, and other diseases.
Noting that deaths have been reported from alcohol poisoning via enemas, an alcohol enema can be used to very quickly instill alcohol into the bloodstream, absorbed through the membranes of the colon. However, great care must be taken as to the amount of alcohol used. Only a small amount is needed as the intestine absorbs the alcohol far more quickly than the stomach.
Preceding an enema for administration of drugs or alcohol, a cleansing enema may first be used for cleaning the colon to help increase the rate of absorption.
All across Mesoamerica ritual enemas were employed to consume psychoactive substances, e.g., balché, alcohol, tobacco, peyote, and other hallucinogenic drugs and entheogens, most notably by the Maya, thus attaining more intense trance states more quickly, and Mayan classic-period sculpture and ceramics depict hallucinogenic enemas used in rituals. Some tribes continue the practice in the present day.
Enemas have also been forcibly applied as a means of punishment.
In the vastly influential Argentine text Facundo, or Civilization and Barbarism, for example, Domingo Faustino Sarmiento describes the use of pepper and turpentine enemas by police forces as a way of discouraging political dissent in post-independence Argentina. Turpentine enemas are very harsh purgatives.
In the Guantanamo Bay Detention Camp, the Senate Intelligence Committee report on CIA torture documented instances of enemas being used by the Central Intelligence Agency in order to ensure "total control" over detainees. Enemas, officials said, are uncomfortable and degrading, The CIA forced nutrient enema on detainees who attempted hunger strikes, documenting "With head lower than torso … sloshing up the large intestines … [what] I infer is that you get a tube up as you can … We used the largest Ewal [sic] tube we had" wrote an officer, and "violent enemas" is how a detainee described what he received.
In arts and literature
In Grace Metalious's novel Peyton Place, the town doctor tells of "a young boy with the worst case of dehydration I ever saw. It came from getting too many enemas that he didn't need. Sex, with a capital S-E-X.". As a teenager, the boy enjoys receiving enemas from his mother.
In Anne Roiphe's novel Torch Song, Marjorie, not knowing how to otherwise address her dysphonia, reminisces on unhappy memories, one of which is her German nurse inflicting on her painful enemas.
In The Right Stuff, during flight training astronaut Alan Shepard retains a barium enema, given two floors away from a toilet, embarrassedly riding a public elevator wearing a hospital gown and holding the enema bag with its tip still inserted in him.
Water Power is a film loosely based on the real-life exploits of Michael H. Kenyon, an American criminal who pleaded guilty to a decade-long series of armed robberies of female victims, some of which involved sexual assaults in which he would give them enemas.
In Sybil, Sybil's psychiatrist, while having taken her for a picnic in the country, heard her re-experience, among other things, her mother having bound her with a broom handle on the kitchen table and suspended her by her feet from the hanging light, in preparation for forcing her to take an enema.
A 365-kilogram (805-pound) brass statue of a syringe enema bulb held aloft by three cherubs stands in front of the "Mashuk" spa in the settlement of Zheleznovodsk in Russia. Inspired by the 15th century Renaissance painter Botticelli, it was created by a local artist who commented that "An enema is an unpleasant procedure as many of us may know. But when cherubs do it, it's all right." When unveiled on 19 June 2008, posted on one of the spa's wall was a banner declaring "Let's beat constipation and sloppiness with enemas." The spa lying in the Caucasus Mountains region, known for dozens of spas that routinely treat digestive and other complaints with enemas of mineral spring water, the director commented "An enema is almost a symbol of our region." It is the only known monument to the enema.
- Alcohol enema
- Bowel management
- Coffee enema
- Colon cleansing
- Dry enema
- Fecal microbiota transplant
- Murphy drip
- Nutrient enema
- Rectal douching
- Tobacco smoke enema
- Transanal irrigation
- Cullingworth, A Manual of Nursing, Medical and Surgical:155
- "enema noun". Noah Webster's American Dictionary of the English Language. Merriam-Webster. Retrieved 15 April 2019.
- "Enema". The Free Dictionary. TheFreeDictionary.com. Retrieved 15 April 2019.
- "enema". Dictionary.com. sAsk.com. Retrieved 15 April 2019.
- "Soapsuds enema". Biology-Online Dictionary. Biology-Online. Retrieved 6 August 2014.
- "Barium enema". MedlinePlus. U.S. Department of Health & Human Services – National Institutes of Health (NIH). Retrieved 6 August 2014.
- Krokowicz, L.; MacKiewicz, J.; Wejman-Matela, A.; Krokowicz, P.; Drews, M.; Banasiewicz, T. (19 October 2014). "Management of traveller's diarrhoea with a combination of sodium butyrate, organic acids, and A-300 silicon dioxide". Przeglad Gastroenterologiczny. U.S. Department of Health & Human Services, National Institutes of Health (NIH). 9 (5): 285–290. doi:10.5114/pg.2014.46164. PMC 4223117. PMID 25396003.
- Bruera, E; Pruvost, M; Schoeller, T; Montegjo, G; Watanabe, S (April 1998). "Proctoclysis for Hydration of Terminally Ill Cancer Patients". Journal of Pain and Symptom Management. 15 (4): 216–9. doi:10.1016/S0885-3924(97)00367-9. PMID 9601155.
- Clemens, Katri E.; Faust, Markus; Jaspers, Birgit; Mikus, Gerd (June 2013). "Pharmacological treatment of constipation in palliative care". Current Opinion in Supportive & Palliative Care. 7 (2): 183–191. doi:10.1097/SPC.0b013e32835f1e17. PMID 23478431. S2CID 3283246.
- "high enema". Medical Dictionary. Merriam-Webster. Retrieved 17 February 2018.
- "Administering an Enema". Care of patients. Ternopil State Medical University. 14 July 2015. Archived from the original on 23 February 2018. Retrieved 17 February 2018.
- Rhodora Cruz. "Types of Enemas". Fundamentals of Nursing Practice. Professional Education, Testing and Certification Organization International. Retrieved 17 February 2018.
- "low enema". Medical Dictionary. Merriam-Webster. Retrieved 17 February 2018.
- Martelli, Mary Elizabeth. "Enema administration". Encyclopedia of Nursing and Allied Health. Archived from the original on 23 January 2008. Retrieved 11 January 2008 – via FindArticles.
- Marilee Schmelzer; Lawrence R. Schiller; Richard Meyer; Susan M. Rugari; Patti Case (November 2004). "Safety and effectiveness of large-volume enema solutions". Applied Nursing Research. 17 (4): 265–274. doi:10.1016/j.apnr.2004.09.010. PMID 15573335.
- "Glycerin Enema". Drugs.com. Retrieved 9 September 2018.
- Bertani E, Chiappa A, Biffi R, Bianchi PP, Radice D, Branchi V, Spampatti S, Vetrano I, Andreoni B (2011). "Comparison of oral polyethylene glycol plus a large volume glycerine enema with a large volume glycerine enema alone in patients undergoing colorectal surgery for malignancy: a randomized clinical trial". Colorectal Disease. 13 (10): e327–e334. doi:10.1111/j.1463-1318.2011.02689.x. PMID 21689356. S2CID 32872781.
- Nicholls, Pam Hufford; Metules, Terri J (April 2001). "Some old-fashioned enemas still work and are still used". RN. 64: 80.
- Ingelfinger, Franz J. (1954). "Treatment of Chronic Constipation". Clinical and Patient Services > Tutorials for Patients & Families. 58 (4): 503–512. Bibcode:1954NYASA..58..503I. doi:10.1111/j.1749-6632.1954.tb45865.x. PMC 5251364. PMID 29831395. Retrieved 12 September 2018.
- Gary M. Vilke; Gerard DeMers; Nilang Patel; Edward M. Castillo (June 2015). "Safety and Efficacy of Milk and Molasses Enemas in the Emergency Department". The Journal of Emergency Medicine. American Academy of Emergency Medicine. 48 (6): 667–70. doi:10.1016/j.jemermed.2015.01.035. PMID 25850633. S2CID 9638496. Retrieved 19 March 2019.
- Kimberley Wallaker; Ezio Fortuna; Stuart Bradin; Michelle Macy; Michelle Hassan; Rachel Stanley (November 2014). "Milk and Molasses Enemas: Clearing Things Up". Journal of Emergency Nursing. The Emergency Nurses Association. 40 (6): 546–551. doi:10.1016/j.jen.2013.08.012. PMID 24182894. Retrieved 19 March 2019.
- "Mineral Oil rectal enema". Drugs, Devices & Supplements. Cleveland Clinic. Retrieved 1 April 2019.
- "ATC (Anatomical Therapeutic Chemical Classification System) – Synopsis". National Institutes of Health. Retrieved 1 February 2020.
- World Health Organization. "Anatomical Therapeutic Chemical (ATC) Classification". World Health Organization. Retrieved 3 January 2022.
- "Structure and principles". WHO Collaborating Centre for Drug Statistics Methodology. 15 February 2018. Retrieved 3 January 2022.
- "ATC/DDD Index 2022: code A06". WHO Collaborating Centre for Drug Statistics Methodology.
- "ATCvet Index 2022: code QA06". WHO Collaborating Centre for Drug Statistics Methodology.
- "NHS Grampian Medicines Management – Laxatives". NHS Grampian Campaign. National Health Service. 2011. Retrieved 4 March 2019.
- Engelhorn, Robert; Seeger, Ernst; Zwaving, Jan H. (2000). "Laxatives". Ullmann's Encyclopedia of Industrial Chemistry. doi:10.1002/14356007.a15_183. ISBN 3527306730.
- "Label: FLEET- bisacodyl enema". Retrieved 3 March 2019.
- Sykes, Nigel P. (2011). "Constipation during active cancer therapy". Supportive Oncology. pp. 177–186. doi:10.1016/B978-1-4377-1015-1.00018-7. ISBN 9781437710151.
- "A06AG Enemas". WHO Collaborating Centre for Drug Statistics Methodology. World Health Organization. 13 December 2018. Retrieved 3 March 2019.
- "Report on Carcinogens, Fourteenth Edition". Report on Carcinogens. National Toxicology Program, Department of Health and Human Services (HHS). November 2016. Retrieved 3 March 2019.
- "Docusate sodium". 18 December 2004.
- "Colace Microenema: Indications, Side Effects, Warnings". Drugs.com.
- "206. Food-grade mineral oil (FAO Nutrition Meetings Report Series 48a)". inchem.org. Archived from the original on 6 August 2007.
- "Sodium Phosphates Enema". Retrieved 3 March 2019.
- "Sodium Phosphate Rectal". Retrieved 3 March 2019.
- "Fleet Enema Side Effects". www.drugs.com. Drugs.com. Retrieved 12 July 2021.
- Stacewicz-Sapuntzakis, Maria; Bowen, Phyllis E.; Hussain, Erum A.; Damayanti-Wood, Bernadette I.; Farnsworth, Norman R. (July 2001). "Chemical Composition and Potential Health Effects of Prunes: A Functional Food?". Critical Reviews in Food Science and Nutrition. 41 (4): 251–286. doi:10.1080/20014091091814. PMID 11401245. S2CID 31159565.
- "ACS :: Cancer Drug Guide: sorbitol". Archived from the original on 30 June 2007.
- "Drugs & Medications".
- "Sorbitol". Retrieved 3 March 2019.
- "Klyx". NHS Grampian Campaign. National Health Service. March 2017. Retrieved 4 March 2019.
- "NHS Grampian – Laxatives". Latest medicine updates. electronic Medicines Compendium (eMC). 16 May 2011. Retrieved 4 March 2019.
- "Microlax Enema". NPS MedicineWise. National Prescribing Service. 2018. Retrieved 4 March 2019.
- W. Lieberman (1964). "Rapid patient preparation for sigmoidoscopy by microenema". American Journal of Proctology. 15: 138–41. PMID 14139893.
- "Micolette Micro-enema". Latest medicine updates. Latest medicine updates. 10 July 2015. Retrieved 4 March 2019.
- Emmanuel, A V; Krogh, K; Bazzocchi, G; Leroi, A-M; Bremers, A; Leder, D; van Kuppevelt, D; Mosiello, G; Vogel, M; Perrouin-Verbe, B; Coggrave, M; Christensen, P (20 August 2013). "Consensus review of best practice of transanal irrigation in adults". Spinal Cord. 51 (10): 732–738. doi:10.1038/sc.2013.86. PMID 23958927.
- , Consensus review of best practice of transanal irrigation in adults A V Emmanuel et al. Spinal Cord 2013.
- "Bowel Management After Spinal Cord Injury". sci-info-pages.com. 2 June 2019.
- Peña A, Guardino K, Tovilla JM, Levitt MA, Rodriguez G, Torres R Bowel management for fecal incontinence in patients with anorectal malformations Pediatr. Surg. 33:1 133–7 1998
- "aGastroenterology Tests and Procedures – Barium Enema". Health Library. Johns Hopkins School of Medicine. Retrieved 1 April 2019.
- "Barium/Gastroview Enema". Our Services. Southwest Medical Center in Liberal, Kansas, USA. Retrieved 1 April 2019.
- Raqib, R.; Sarker, P.; Mily, A.; Alam, N. H.; Arifuzzaman, A. S.; Rekha, R. S.; Andersson, J.; Gudmundsson, G. H.; Cravioto, A.; Agerberth, B. (10 May 2012). "Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial". BMC Infectious Diseases. U.S. Department of Health & Human Services, National Institutes of Health (NIH). 12: 111. doi:10.1186/1471-2334-12-111. PMC 3447723. PMID 22574737.
- Tremayne, Vincent (23 September 2009). "Proctoclysis: emergency rectal fluid infusion". Nursing Standard. 24 (3): 46–48. doi:10.7748/ns2009.09.24.3.46.c7271. PMID 19856644.
- Bakken, Johan S.; Borody, Thomas; Brandt, Lawrence J.; Brill, Joel V.; Demarco, Daniel C.; Franzos, Marc Alaric; Kelly, Colleen; Khoruts, Alexander; Louie, Thomas; Martinelli, Lawrence P.; Moore, Thomas A.; Russell, George; Surawicz, Christina; Fecal Microbiota Transplantation Workgroup (December 2011). "Treating Clostridium difficile Infection With Fecal Microbiota Transplantation". Clinical Gastroenterology and Hepatology. 9 (12): 1044–1049. doi:10.1016/j.cgh.2011.08.014. PMC 3223289. PMID 21871249.
- Olga C. Aroniadis; Lawrence J. Brandt (January 2013). "Fecal microbiota transplantation: past, present and future". Current Opinion in Gastroenterology. Lippincott Williams & Wilkins. 29 (1): 79–84. doi:10.1097/MOG.0b013e32835a4b3e. PMID 23041678. S2CID 39943619.
- "nutrient enema". The Free Dictionary. TheFreeDictionary.com. Retrieved 1 May 2019.
- Mattern, Susan P. (2008), Galen and the Rhetoric of Healing, Johns Hopkins University Press, Maryland, USA: Johns Hopkins University Press, pp. 31, 145, 149, ISBN 978-0-8018-8835-9
- Short AR, Bywaters HW (June 1913). "Amino-Acids and Sugars in Rectal Feeding". Br Med J. 1 (2739): 1361–1367. doi:10.1136/bmj.1.2739.1361. JSTOR 25302025. PMC 2299894. PMID 20766702.
- Mackenzie JW (March 1943). "The nutrient enema". Arch. Dis. Child. 18 (93): 22–27. doi:10.1136/adc.18.93.22. PMC 1987791. PMID 21032242.
- "War Department Technical Manual Hospital Diets" (PDF). Technical Manuals. United States Department of War. 13 October 1941. Retrieved 1 May 2019.
- "Enemas during labour". Cochrane Database of Systematic Reviews: Plain Language Summaries. National Institutes of Health (NIH). 4 July 2013. Retrieved 14 June 2016.
- "Fleet Enema Rectal: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing". WebMD.
- "Colon Hydrotherapy". Aetna IntelliHealth. 1 July 2005. Archived from the original on 7 August 2007. Retrieved 23 April 2007.
- Eliakim R, Karmeli F, Rachmilewitz D, Cohen P, Zimran A (4 January 2004). "Ozone Enema: A Model of Microscopic Colitis in Rats". Digestive Diseases and Sciences. 46 (11): 2515–20. doi:10.1023/A:1012348525208. PMID 11713963. S2CID 11489322.
- Ori Y, Rozen-Zvi B, Chagnac A, Herman M, Zingerman B, Atar E, Gafter U, Korzets A (2012). "Fatalities and Severe Metabolic Disorders Associated With the Use of Sodium Phosphate Enemas". Archives of Internal Medicine. 172 (3): 263–5. doi:10.1001/archinternmed.2011.694. PMID 22332159.
- "enema (n.)". Online Etymology Dictionary. Douglas Harper of the LNP Media Group. Retrieved 15 April 2019.
- "clyster (n.)". Online Etymology Dictionary. Douglas Harper of the LNP Media Group. Retrieved 29 December 2019.
- Benjamin Rush (1769). Medical observations and inquiries. By a Society of Physicians in London. Vol. 3 (The Second ed.). London. pp. 250, 251, 252. Retrieved 22 January 2022.
- Magner, A History of Medicine:31
- Magner, A History of Medicine:30
- Magner, A History of Medicine:26
- Friedenwald & Morrison, 'Part I:75-76
- F. J. Carod-Artal (1 July 2011). "Hallucinogenic drugs in pre-Columbian Mesoamerican cultures". Neurología. Science Direct. 30 (1): 42–49. doi:10.1016/j.nrleng.2011.07.010. PMID 21893367.
- Parsons and Carlson:92
- de Smet PA, Hellmuth NM (1986). "A multidisciplinary approach to ritual enema scenes on ancient Maya pottery". J Ethnopharmacol. 16 (2–3): 213–62. doi:10.1016/0378-8741(86)90091-7. PMID 3528674.
- Hurt, Raymond; Barry, J. E.; Adams, A. P.; Fleming, P. R. (1996), The History of Cardiothoracic Surgery from Early Times, Informa Health Care, p. 120, ISBN 978-1850706816
- Nordenskiold, Erland (1929), "The American Indian as an Inventor", Journal of the Royal Anthropological Institute, 59: 277, doi:10.2307/2843888, JSTOR 2843888
- Friedenwald & Morrison, Part II:261
- Friedenwald & Morrison, Part II:240
- Friedenwald & Morrison, Part I:77
- Page, Sidney G. (2 April 1955). "A Comparative Clinical Study of Several Enemas". Journal of the American Medical Association. 157 (14): 1208–1210. doi:10.1001/jama.1955.02950310034008. PMID 14353661.
- Friedenwald & Morrison, 'Part I:77–80
- Friedenwald & Morrison, 'Part I:71
- Scarborough, The Drug Lore of ASCLEPIADES of Bithynia:44
- Scarborough, The Drug Lore of ASCLEPIADES of Bithynia:46
- Soranus (1956). Soranus' Gynecology. Translated by Owsei Temkin. JHU Press. pp. 62–67. ISBN 9780801843204.
- "Information Sheet:21 Enemas" (PDF). Information Sheets. Museum of the Royal Pharmaceutical Society, London. Archived from the original (PDF) on 6 March 2016. Retrieved 3 January 2020.
- Dunn, P. M. (1991). "Francois Mauriceau (1637-1709) and maternal posture for parturition". Archives of Disease in Childhood. 66 (1 Spec No): 78–79. doi:10.1136/adc.66.1_Spec_No.78. PMC 1590357. PMID 1996901.
- Friedenwald & Morrison, Part II:245
- Sterling Haynes (December 2012). "Special feature: Tobacco smoke enemas". British Columbia Medical Journal. Doctors of BC. Retrieved 29 March 2019.
- Saint-Simon, Memoires, vol. 10, ch. 4.
- "Fleet" (PDF). A Supplement to The News & Advance. The News & Advance. 27 April 2014. Archived from the original (PDF) on 3 January 2020. Retrieved 3 January 2020.
- Locke, G.Richard; Pemberton, John H.; Phillips, Sidney F. (December 2000). "AGA technical review on constipation". Gastroenterology. 119 (6): 1766–1778. doi:10.1053/gast.2000.20392. PMID 11113099.
- "Subpart F—Therapeutic Devices Sec. 876.5220 Colonic irrigation system". Code of Federal Regulations, Title 21 Food and Drugs, Subchapter H – Medical Devices, Part 876 – Gatroenterology-Urology Devices. FDA. 1 April 2007.
- Department of Health and Human Services (21 July 1999). "Warning letter to Dotolo Research Corp" (reprint by Casewatch). FDA. Retrieved 31 December 2007.
- Whorton J (2000). "Civilisation and the colon: constipation as the "disease of diseases"". BMJ. 321 (7276): 1586–9. doi:10.1136/bmj.321.7276.1586. PMC 1119264. PMID 11124189.
- Ernst, E. (June 1997). "Colonic Irrigation and the Theory of Autointoxication: A Triumph of Ignorance over Science". Journal of Clinical Gastroenterology. 24 (4): 196–198. doi:10.1097/00004836-199706000-00002. PMID 9252839.
- Kaiser (1985). "The Case Against Colonic Irrigation". California Morbidity (38).
- Chen TS, Chen PS (1989). "Intestinal autointoxication: a medical leitmotif". Journal of Clinical Gastroenterology. 11 (4): 434–41. doi:10.1097/00004836-198908000-00017. PMID 2668399.
- "Dr. John Harvey Kellogg". Great American Quacks. Museum of Quackery. Retrieved 12 February 2018.
- Sophie Norri; Lucy Clarke-Billings (8 August 2017). "Secret Facebook group reveals how parents use bleach enemas on autistic children in bid to 'cure' disability". Daily Mirror. Reach plc. Retrieved 24 March 2019.
- Toby Meyjes (7 August 2017). "Mother 'investigated for giving son bleach enema to "cure" his autism'". Metro (British newspaper). DMG Media. Retrieved 24 March 2019.
- Lisa Bartley (29 October 2016). "Group of SoCal parents secretly try to cure kids with autism using bleach". ABC 7 News. American Broadcasting Company. Retrieved 24 March 2019.
- Frances Ryan (13 July 2016). "The fake cures for autism that can prove deadly". The Guardian. Retrieved 24 March 2019.
- "The truth about chlorine dioxide and other miracle cures for autism". Health24. 11 November 2015. Retrieved 24 March 2019.
- Sidney Baker; Ali Carine; Suruchi Chandra; Kelly M. Barnhill; John Green; Maya Shetreat-Klein; Vicki Kobliner; Dana Laake; Elizabeth Mumper; Nancy O'Hara; William Parker (12 July 2015). "Warning Against Chlorine Dioxide Use". Autism is Treatable. Autism Research Institute. Archived from the original on 30 March 2019. Retrieved 24 March 2019.
- "PubChem Database. Chlorine dioxide, CID=24870". PubChem. National Center for Biotechnology Information. Retrieved 24 March 2019.
- "The Parents Who Give Their Children Bleach Enemas to 'Cure' Them of Autism". vice.com. 12 March 2015. Retrieved 24 March 2019.
- "FDA Warns Consumers of Serious Harm from Drinking Miracle Mineral Solution (MMS)". U.S. Food and Drug Administration. 3 February 2011. Archived from the original on 3 February 2011. Retrieved 24 March 2019.
- "Parents Are Making Their Children Drink Bleach to 'Cure' Them of Autism". Newsweek/Yahoo News. 22 March 2019.
- Jim Humble (2006). The Miracle Mineral Solution of the 21st Century. Jim Humble. (self published)
- Jensen, Erik (9 January 2010). "Deadly chemical being sold as miracle cure". The Sydney Morning Herald. Retrieved 24 March 2019.
- "IFRC strongly dissociates from the claim of a 'miracle' solution to defeat malaria" (Press release). International Federation of Red Cross and Red Crescent Societies. 15 May 2013. Archived from the original on 24 February 2021. Retrieved 24 March 2019.
- Shils ME, Hermann MG (April 1982). "Unproved dietary claims in the treatment of patients with cancer". Bull N Y Acad Med. 58 (3): 323–40. PMC 1805327. PMID 7052177.
- Lee CJ, Song SK, Jeon JH, Sung MK, Cheung DY, Kim JI, Kim JK, Lee YS (2008). "Coffee enema induced acute colitis". The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi. 52 (4): 251–254. PMID 19077527.
- "Colon Therapy". American Cancer Society. 11 January 2008. Retrieved 13 May 2011.
- Margolin KA, Green MR (1984). "Polymicrobial enteric septicemia from coffee enemas". The Western Journal of Medicine. 140 (3): 460. PMC 1021723. PMID 6710988.
- Eisele JW, Reay DT (1980). "Deaths related to coffee enemas". JAMA: The Journal of the American Medical Association. 244 (14): 1608–1609. doi:10.1001/jama.1980.03310140066036. PMID 7420666.
- Keum B, Jeen YT, Park SC, Seo YS, Kim YS, Chun HJ, Um SH, Kim CD, Ryu HS (2010). "Proctocolitis Caused by Coffee Enemas". The American Journal of Gastroenterology. 105 (1): 229–230. doi:10.1038/ajg.2009.505. PMID 20054322. S2CID 19156781.
- "Livingston-Wheeler Therapy". Memorial Sloan Kettering Cancer Center. 9 May 2011. Retrieved 13 May 2011.
- William T. Jarvis, Ph.D., National Council Against Healthcare Fraud, "Cancer Quackery". Accessed 11 July 2012.
- Centers for Disease Control (CDC) (1981). "Campylobacter sepsis associated with "nutritional therapy"--California". MMWR Morb. Mortal. Wkly. Rep. 30 (24): 294–5. PMID 6789105.
- Keum B, Jeen YT, Park SC, Seo YS, Kim YS, Chun HJ, Um SH, Kim CD, Ryu HS (2010). "Proctocolitis caused by coffee enemas". Am. J. Gastroenterol. 105 (1): 229–30. doi:10.1038/ajg.2009.505. PMID 20054322. S2CID 19156781.
- Eisele JW, Reay DT (October 1980). "Deaths related to coffee enemas". JAMA. 244 (14): 1608–9. doi:10.1001/jama.1980.03310140066036. PMID 7420666.
- "The Gerson Institute — Alternative Cancer Treatment". Archived from the original on 1 April 2003.
- Weitzman S (1998). "Alternative Nutritional Cancer Therapies". International Journal of Cancer. 78 (S11): 69–72. doi:10.1002/(SICI)1097-0215(1998)78:11+<69::AID-IJC20>3.0.CO;2-7. PMID 9876483. S2CID 20633344.
- Cassileth B (February 2010). "Gerson regimen". Oncology (Williston Park, N.Y.). 24 (2): 201. PMID 20361473.
- Paraphilias from Psychology Today
- Denko, JD. (April 1973). "Klismaphilia: enema as a sexual preference. Report of two cases". Am J Psychother. 27 (2): 232–50. doi:10.1176/appi.psychotherapy.19184.108.40.206. PMID 4704017.
- Agnew, 1982
- Denko, JD. (April 1976). "Amplification of the erotic enema deviance". Am J Psychother. 30 (2): 236–55. doi:10.1176/appi.psychotherapy.19220.127.116.11. PMID 937588.
- Brame et al., Different loving – The World of Sexual Dominance and Submission:517
- Kinsey, Alfred Charles (1953), Sexual Behavior in the Human Female, Bloomington, Indiana, U.S.A.: Indiana University Press, ISBN 978-0-253-33411-4
- , Klismaphilia:76
- Brame et al., Different loving – The World of Sexual Dominance and Submission:513,516
- Agnew, 2000:74,77,78,79
- Brame et al., Different loving – The World of Sexual Dominance and Submission:515,516,520
- Brame et al., Different loving – The World of Sexual Dominance and Submission:513,517
- Agnew, 2000:76
- Javanbakht, Marjan; Stahlman, Shauna; Pickett, Jim; LeBlanc, Marc-André; Gorbach, Pamina M (December 2014). "Prevalence and types of rectal douches used for anal intercourse: results from an international survey". BMC Infectious Diseases. 14 (1): 95. doi:10.1186/1471-2334-14-95. PMC 4015843. PMID 24555695.
- Carballo-Diéguez, Alex; Bauermeister, José A.; Ventuneac, Ana; Dolezal, Curtis; Balan, Ivan; Remien, Robert H. (2007). "The Use of Rectal Douches among HIV-uninfected and Infected Men who Have Unprotected Receptive Anal Intercourse: Implications for Rectal Microbicides". AIDS and Behavior. 12 (6): 860–866. doi:10.1007/s10461-007-9301-0. ISSN 1090-7165. PMC 2953367. PMID 17705033.
- Schreeder, M. T.; Thompson, S. E.; Hadler, S. C.; Berquist, K. R.; Zaidi, A.; Maynard, J. E.; Ostrow, D.; Judson, F. N.; Braff, E. H.; Nylund, T.; Moore, J. N.; Gardner, P.; Doto, I. L.; Reynolds, G. (1982). "Hepatitis B in Homosexual Men: Prevalence of Infection and Factors Related to Transmission". Journal of Infectious Diseases. 146 (1): 7–15. doi:10.1093/infdis/146.1.7. ISSN 0022-1899. PMID 7086206.
- de Vries, Henry J.C.; van der Bij, Akke K.; Fennema, Johan S.A.; Smit, Colette; de Wolf, Frank; Prins, Maria; Coutinho, Roel A.; MorrÉ, Servaas (2008). "Lymphogranuloma venereum proctitis in men who have sex with men is associated with anal enema use and high-risk behavior". Sexually Transmitted Diseases. 35 (2): 203–208. doi:10.1097/OLQ.0b013e31815abb08. PMID 18091565. S2CID 2065170.
- "The Enema Within". Darwin Awards. 2008. Retrieved 11 January 2008.
- de Boer AG, Moolenaar F, de Leede LG, Breimer DD (1982). "Rectal drug administration: clinical pharmacokinetic considerations". Clin Pharmacokinet. 7 (4): 285–311. doi:10.2165/00003088-198207040-00002. PMID 6126289. S2CID 41562861.
- Diamond, Jared M. (1992). The Third Chimpanzee: The Evolution and Future of the Human Animal (P.S.). New York, N.Y.: Harper Perennial. p. 432. ISBN 978-0-06-084550-6.; pp. 201
- "Basti: Medicated Enema Therapy".
- "Ribbons and Rituals". In Problems in Modern Latin American History. Ed. Chasteen and Wood. Oxford, UK: Scholarly Resources, 2005. p. 97
- "Turpentine enema". Biology-Online Dictionary. Biology-Online. Retrieved 20 April 2019.
- Rushe, Dominic; MacAskill, Ewen; Cobain, Ian; Yuhas, Alan; Laughland, Oliver (9 December 2014). "Rectal rehydration and waterboarding: the CIA torture report's grisliest findings". The Guardian. Retrieved 13 March 2015.
- Neil A. Lewis (1 January 2005). "Fresh Details Emerge on Harsh Methods at Guantánamo". Archives – 2005. The New York Times. Retrieved 20 April 2019.
- "Controversial 'rectal feeding' technique used to control detainees' behaviour". The Guardian. 9 December 2014. Retrieved 20 April 2019.
- The Editorial Board (5 June 2015). "A Detainee Describes More C.I.A. Torture". Editorial. The New York Times. Retrieved 22 April 2019.
- Shaw, Carl A. (2014). Satyric Play: The Evolution of Greek Comedy and Satyr Drama. Oxford, England: Oxford University Press. p. 15. ISBN 978-0-19-995094-2.
- William Shakespeare (1603). "Othello, the Moore of Venice". Retrieved 27 March 2019.
- Friedenwald & Morrison, Part I:99
- Magner, A History of Medicine:218
- Molière (10 May 2018). "?Molière at Versailles". Theater in Translation. The Mercurian. Retrieved 18 July 2020.
- Orwell, George (1949). 1984. New York: Harcourt, Brace and Company. ISBN 9780151660353.
- Thomas Mallon; Anna Holmes (4 March 2014). "What's It Like Reading 'Peyton Place' Today?". Book Review. The New York Times. Retrieved 18 April 2019.
- R. Saint Claire (20 September 2016). "My Return to Peyton Place". Ex Libris Regina. R. Saint Claire. Archived from the original on 19 February 2019. Retrieved 18 April 2019.
- Debbie Nathan (14 October 2011). "A Girl Not Named Sybil". The New York Times Magazine. Retrieved 21 April 2019.
- Julian Moynahan (9 January 1977). "Sad in Greenwich Village, glad in Atlantic City". Book Reviews. The New York Times. Retrieved 27 March 2019.
- Anne Sexton (11 July 2006). "Cripples And Other Stories - Poem by Anne Sexton". Poem Hunter. poemhunter. Retrieved 18 April 2019.
- Vincent Canby (21 October 1983). "'Right Stuff,' on astronauts". Film. The New York Times. Retrieved 27 March 2019.
- "The Right Stuff". Teach with Movies. Retrieved 27 March 2019.
- "The Right Stuff". IMDb. Retrieved 27 March 2019.
- "Water Power". Adult DVD Talk.
- "Sybil". Behavior Genetics (journal). Springer Science+Business Media. 1976. Retrieved 21 April 2019.
- Mick Ireland (9 June 1975). "Enema bandit suspect faces hearing today". Illinois Digital Newspaper Collections. University of Illinois at Urbana–Champaign. Retrieved 27 March 2019.
- "Russian monument to enemas inspired by Botticelli". Reuters Life!. Reuters. 19 June 2008. Retrieved 12 April 2019.
- "Enema monument unveiled Russian resort". NBC News. 19 June 2008. Retrieved 12 April 2019.
- "Monument to Enemas". Places. Atlas Obscura. Retrieved 12 April 2019.
- Agnew, Jeremy (October 1982). "Klismaphilia—A Physiological Perspective". American Journal of Psychotherapy. 36 (4): 554–566. doi:10.1176/appi.psychotherapy.1918.104.22.1684. PMID 7158678.
- Agnew, Jeremy (January 2000). "Klismaphilia". Venereology. 13 (2).
- Brame, Gloria; Brame, William D.; Jacobs, Jon (1993). Different loving – The World of Sexual Dominance and Submission. Villard Books. ISBN 978-0-6797-6956-9.
- Cullingworth, Charles James (1883). A Manual of Nursing, Medical and Surgical. Cambridge, England: Cambridge University Press (published 2009). ISBN 978-1-4590-1939-3.
- Friedenwald, Julius; Morrison, Samuel (January 1940). "The History of the Enema with Some Notes on Related Procedures (Part I)". Bulletin of the History of Medicine. Johns Hopkins University Press. 8 (1): 68–114. JSTOR 44442727.
- Friedenwald, Julius; Morrison, Samuel (February 1940). "The History of the Enema with Some Notes on Related Procedures (Part II)". Bulletin of the History of Medicine. Johns Hopkins University Press. 8 (2): 239–276. JSTOR 44442727.
- Magner, Lois (1992). A History of Medicine. Boca Raton, Florida: CRC Press. ISBN 978-0-8247-8673-1.
- Parsons, Lee Allen; Carlson, John B. (1988). The Face of Ancient America: The Wally and Brenda Zollman Collection of Precolumbian Art. Indianapolis, Indiana, United States: Indianapolis Museum of Art. ISBN 978-0-936260-24-2.
- Scarborough, John (1975). "The Drug Lore of ASCLEPIADES of Bithynia". Pharmacy in History. 17 (2): 43–57. JSTOR 41108902. PMID 11609880.
"A professional nursing instructional video demonstrating administering a cleansing enema". Taber's Medical Dictionary. K. A. Davis Company. Retrieved 17 July 2014.