Used as London point of departure for stage coaches from the 1650s onwards.
See advert in Mercurius Politicus, April 8th 1658, quoted in Martim de Albuquerque's "Notes and Queries" No. 14, page 146, published 1850 :
"All persons who desire to travel into the cities, towns and roads, herein herafter mentioned ... let them repair to the George Inn at Holborn Bridge, London, and thence they shall be in good coaches with good horses, upon every Monday, Wednesday and Friday, at and for reasonable rates"
Pepys took his wife there on Monday 28th July 1662 to take the coach to Bugden (Buckden in Cambridgeshire).
Chart showing the number of references in each month of the diary’s entries.